Love those pranks!
A good friend of mine had a few roommates and a mutual friend of theirs would quite often come over drunk and high. He would eat a bunch and then pass out on a bed. So they kinda got tired of this after about 3 months of this happening 6 out of 7 days a week. So they all made some cookies.. they weren't normal cookies, they were filled with laxative. And so he came home and did the same thing. but he ate the whole batch of laxitive cookies. he went and passed out. You can imagine the rest.
Another prank pulled by them on the same guy. Came in, passed out. He was a super hairy guy, my friend bought some Nair.... they got rid of every hair from neck down to toes. (yes even inside his underwear.) He finally realized he should probably stop passing out at their place..