My take on that.
Look at the new GTX580 that just came out. They're running cooler than GTX480, while being about 20% to 30% more powerful.
some already come with waterblocks...expensive tho. Look for EVGA GTX580 FTW Hydrocopper...way too expensive for my blood.
I don't what computer you own now, but with AMD "Bulldozer" 8 core CPUs coming in March next year, and Intel "SandyBridge" CPUs coming in next year also, It might be a good idea to hold off for a few months...my 2 cents...
For SSDs, I'd rather go single SSD for TRIM support, than a RAID...a 120GB would be more than enough for OS drive...no need to fork 600$ for a 240GB SSD! Go OCZ Vertex 2 Sandforce! 3 year warranty and the best customer support (their forum is really alive)..
HAF-X is nice, you might just need a 8-pin PCI-E extension cable to route the 8-pin ATX cable to the mobo.
Good luck...that a whole lot of money you're planning to spend!
I'm waiting for Bulldozer or Sandy bridge, see how they fare, before I replace my OCed Q9550 @ 3.8GHz / HD5870 combo...