There is some great advice above....
1. What is the main purpose of this firearm
2. Price
3. Make sure your hand fits the firearm...do you have a big, medium or small hand
4. Will you have children in your home?
5. If you use this for home protection? If so I would push you toward hollow point ammo verses full metal jacket
My wife has a Smith & Wesson 38 with a laser sight...perfect for her dainty hands...not so much for my monster paws...also a easy and quick point and kill pistol
I carry a XD 45...fits my hand well with it "double stack" mags...multiple safety's...in my night stand I keep a 1911 45...very safe gun...multiple configurations with hammer and safety's making it impossible for a child to shoot.
PM me with the answers above and I will be happy to give you my advise...
johnny