Ok so 1 st you are trying to get to many HD running OS off of 1 machine. You do not need this I'm sure even if you thought that 5 would be the perfect back up there still in the same machine thats not a back up. So if you have to like me have a different OS for what ever reason that would mean 3 different OS xp win 7 and win 8. that leaves 2 hd running crap, format and use as storage period no need to have two os doing the same shit. If its window keys your worried about give them up you don't need them or the problem of keeping them updated. So you now have 3. You can get 2 to run so one is having problems. Back up the data format and reload windows on the HD that is giving you issues . That will solve your problem. So you now have 3 OS on 5 HD. Why ?? I can see having 2 HD running an os if one dies you can go to the next but 3 is over kill. So format the 3 biggest HD and use them for storage. Run win 7 on one and the other have 7 on it to update to 10. You have a brand new system and if you set it up this way you should have a long go at no problems. BTW al that is still in one machine so its really not any backup at all. Get some external drive cases and olny use 3 HD in the machine and 2 for external backup. If your up to that many HD you have to go this way. Running OS on HD and thinking there good back ups is a well pain and the OS is taking up space where you can store shit. So now we have to hook them up your new MB will allow 6 sata drives you now need 5 cables 3 id you pull 2 HD and use them externally. And to switch between hd with OS on them you tap the f8 key at teh MB logo and it will give you the option of what HD to load. Thats kinda basic but its is what it is.