YouSendIt is one of the most popular and contemporary file sharing services.
As for email programs, I use Thunderbird, from Mozilla - makers of Firefox. It, too, has an expiration date stamped on it, though. As I understand, one more major update is planned, then the Thunderbird project will be mothballed. They also site the preponderance of web-based email services as the final nail in the coffin of further development. Sad because Thunderbird is a BRILLIANT email client. I've used it for at least the past 7 years or so. Its evolved nicely. That said, and because I have a smartphone, I'm even using my gmail accounts more than ever before. But that's for personal emails. Business emails are another matter entirely.