Majbasil

Have you ever made CINCINNATI CHILI?

YIKES! OK so, you all are in shock and rightly so, but nowadays there are wonderful treatments to kick cancer's butt! My father in law (stubborn man who never went to doctors) had all the symptoms of colon cancer and only went to dr when he literally could not poop anymore. Initial doctor said "Oh, too far advanced, you have about 3 months, say your goodbyes." Flash forward 5 years, he was still alive and walking and living his life, yes, it had altered and had to have a bag at that point attached to his side (eww) but he waited till way longer than normal nowadays. They did surgery and some radiation in strategic areas, it had metastasized to everywhere by the time he went to any doctor about it, so sad but he could have prevented his situation imho. That was hmmm 20 or so years ago. THINGS HAVE CHANGED SINCE THEN. Immunotherapies, better targeted radiation equipment and techniques... I met a lovely women in her early 40's who was healthy and ate well enough, who much to her surprise was diagnosed with colon cancer stage 4! By the time I met her, she had undergone all the necessary treatments and such and was back to living a normal life! So do not despair! Be sympathetic and helpful, but be very positive and hopeful! A biopsy will help them determine how to treat this. PD-1 inhibitors Pembrolizumab (Keytruda), nivolumab (Opdivo), and Dostarlimb (Jemperli) are drugs that target PD-1, a protein on immune system cells called T cells that normally help keep these cells from attacking other cells in the body. By blocking PD-1, these drugs boost the immune response against colorectal cancer cells. They are only given if the tumor has had findings of dMMR or MSI-H. Pembrolizumab can be given alone. It is given as an intravenous (IV) infusion every 3 or 6 weeks. Nivolumab can be given alone or with ipilimumab (see below). It is typically given by itself as an IV infusion every 2 or 4 weeks. If it is used along with ipilimumab, then it is typically given every 3 weeks. Dostarlimab can be given alone. It is given as an intravenous (IV) infusion every 3 weeks for 4 treatments, and then given at a higher dose every 6 weeks. This drug is not approved specifically to treat colorectal cancer at this time. It is approved to treat other types of cancer, but doctors can prescribe it off-label for colorectal cancer. Still, it’s important to check with your insurance provider before getting this drug to make sure it is covered. CTLA-4 inhibitor Ipilimumab (Yervoy) is another drug that boosts the immune response, but it has a different target. It blocks CTLA-4, another protein on T cells that normally helps keep them in check. This drug can be used along with nivolumab (Opdivo) to treat colorectal cancer, but it’s not used alone. It is given as an intravenous (IV) infusion, usually once every 3 weeks for 4 treatments. For people with either early- or advanced-stage colorectal cancer, immunotherapy is now a cornerstone of treatment if the tumor has findings of dMMR (deficient mismatch repair) or MSI-H (microsatellite instability-high).

You going where? Looked it up.... https://en.wikipedia.org/wiki/Sanirajak remote, cold, way, way, way up there... Have fun and please take photos and share!

So we had our special "2024 Solar Eclipse" sunglasses, had our chairs set up perfectly in the backyard, raincoats on (IT WAS STORMING), and could not even find the sun! Meanwhile, my kids traveled to Solar Eclipse parties in different parts of the country and had a blast, took great photos... SO. I have decided. We are off to Western Iceland for the Aug 12, 2026 Total Solar Eclipse (volcanos be damned.) I have been to Iceland before, it was June, and froze my butt off... it was windy, it was bleek and grey, sleeting the whole time, no flowers, no greenery, just greys, just sayin. https://skyandtelescope.org/astronomy-news/plan-now-for-the-2026-total-solar-eclipse-in-europe/

Hey Alton, I must say, I like your recipes... If you are not the real and only ALTON BROWN Chef, ignore lol https://altonbrown.com/ https://altonbrown.com/videos/alton-browns-thanksgiving-101/ https://altonbrown.com/videos/alton-browns-green-bean-casserole-2-0/ AND THIS link is for RAVEN, who loves his gin and tonic... https://altonbrown.com/videos/the-life-and-times-of-gin-and-tonic/

seriously, don't buy pickles that have that bright yellow look to them! --> Sure, pickles are naturally green, just not the vibrant green you often see in jars. To keep cucumber skins from fading during their stint on supermarket shelves, manufacturers often add yellow coloring to amplify their natural color. Some food companies use turmeric (a yellow spice added to curry) and some use tartrazine, an artificial lemon-yellow dye derived from coal tar that may cause mutations in cell DNA. Tartrazine also goes by the names FD&C; Yellow #5 and Yellow 5. Read labels and choose pickle brands without added synthetic color. A few, like Trader Joe’s brand pickles, are dye-free. If you can’t give up your neon green dills, sours and sweets, opt for those containing natural coloring this is what I buy --> https://igourmet.com/products/barrel-pickles

It's mane, like horse hair, right? NO? OOPS OK Man-E

I am so so sorry! I was glued to my youtube all night watching in horror as those tornadoes formed and spread havoc to everyone in their paths. So glad everyone is safe, the cleanup and damage, so stressful for your community and the other areas affected by all those tornados, saw some were even sister tornados. This is our new norm, I think, bigger storms, badder droughts, higher temps, etc. My in-laws had an underground tornado/storm shelter in their backyard, loaded with supplies when they lived in "tornado alley", which was comforting for them to know if/when a bad one was coming they had a place to go to. Heck of a Spring for you all, so sorry. This is the youtube I watch when there is crazy weather --> https://www.youtube.com/@RyanHallYall

I am so so sorry! You have had such a sad year. Big hug.

WELL HOW CUTE ARE YOU BOYS? ADORABLE

You are living the life, great read thanks.

As I lived in Ashburn for years, I know the area extremely well. Been following this (as well as the plane landing on Ashburn (Loudoun County) Parkway last month) and it is so so so very tragic this happened! OMG! Not sure if folks realize that Loudoun County, VA has an all VOLUNTEER Fire Dept. These are heros all of them. That one of yours died, and so many others were burned and wounded by debris is heartbreaking. I am so sorry for you, for Sterling, for all the firemen/women of Loudoun County, apparently even a Fairfax fireman was hurt (Sterling is not far from the Fairfax County border.) Youtube is the best way to get info about this, here are some links -->

you might have to run this many times depending on how burnt in it is, might take days? BUT it works... kinda... just depends on how bad the burn in is. ALSO, find other similar ones like this and try them, switch it up. GOOD LUCK (We ended up buying a new TV as we realized we could use a bigger and better TV in that room than that one we just fixed using this trick. SO donated it.)

lol